Advantages of Using a Vacuum Mixer
Vacuum mixers can be used for a wide variety of applications, from mixing silicone, epoxy and PDMS to dispersing powdered active ingredients into liquids. They reduce oxidation, make the process faster and easier, and improve quality.
The VPM2 can store 99 programs, while the VPM Mini allows for varying RPMs and mixing time in five second increments.
Homogenization
Homogenization is an essential process for creating a more uniform product. It helps to eliminate air bubbles and ensure that all ingredients are evenly distributed. Consequently, it increases the product’s effectiveness. In addition, it can help to preserve the original properties of a product.
Several physical phenomena contribute to homogenization, including shear force, turbulence, and cavitation. However, a vacuum mixer is particularly useful for the process because it allows the liquid to be mixed at lower temperatures. This can reduce the likelihood of bacterial contamination, which is particularly important in medical and food applications.
In most cases, a homogenizer is used for the purpose of dispersing solid active materials into suspensions or emulsions. Homogenization is also an effective method for reducing the viscosity of a solution by increasing its interfacial area. The homogenization process may also be utilized to break up fat globules in products with high fat content. In this case, a homogenizer is typically equipped with either a blade type or rotor-stator homogenizing system. Both types of systems can be operated under a variety of pressures, ranging from 10 to 30 MPa (100-300 bar). The higher the pressure, the more finely the particle size is reduced.
Fermentation and Synthesis
Biological fermentation is an alternative to chemical synthesis in the production of many natural products. Its advantages include reduced vacuum mixer costs, safer working environments and the avoidance of the use of toxic raw materials. It also allows for the synthesis of complex heterocyclic compounds that are inaccessible through typical organic syntheses.
However, industrial microbial fermentation still relies heavily on conventional refined sugar-based feedstocks that are expensive and not sustainable in the long term. Further innovation is needed in strain development to uncover new workhorse microorganisms and visionary regulatory leadership to streamline commercial adoption of these candidates.
A vacuum mixer is an essential piece of equipment for this application, as it can prevent air bubbles from forming in wet or dry preparations. It can degassize a variety of materials, including powders, jells, pastes, plastics resins and epoxies. It can also help improve the stability of solid drugs by removing oxygen and moisture from the formulation. This will enhance the performance of the final product and improve its durability. The machine can also be used to mix wet and dry preparations and disperse them evenly.
Evaporation/Dehumidification
Many preparations, including epoxies and gels, benefit from being mixed under vacuum. This prevents the incorporation of air bubbles and promotes a more thorough degassing process. This can greatly shorten processing time and improve the quality of the final product.
This technique can also be used in the manufacturing of a wide variety of materials, including silicones, PDMS, other polymers, liquids and ingredients. This is especially useful when producing a product that requires a high level of precision, such as dental cements and plasters.
A common application is the mixing of powdered active ingredients in liquids, such as lithium battery anode and cathode material slurries or ceramic slurries. This prevents the formation of insoluble agglomerates and reduces process times, making it easier to achieve homogeneous distribution and encapsulation. It can also be used in the manufacture of drugs that must be mixed under vacuum to prevent air incorporation. This can help the drug reach the desired destination in the patient’s body and ensure it is fully absorbed. This can improve treatment efficacy and reduce the risk of side effects.
Impregnation
Vacuum mixing helps ensure that materials, particularly powders and liquids, are fully dispersed without air bubbles. This makes for mixer manufacturer a smoother, more homogeneous mixture that performs better than one hand-mixed or batch-processed.
Mixing under vacuum conditions also prevents the formation of air pockets in the final product, reducing the possibility of failure due to oxidation. This is especially important in the manufacturing of cements and amalgams for medical applications.
In the case of solid surface fabrication, the ability to mix under vacuum reduces oxidation, improves quality, shortens processing time and increases machine availability. For example, a vacuum mixer eliminates the need for a separate deaeration step after matrix blending, allowing for fast, efficient processing of void-free cast solid surface products. The Vac-U-Mixer can also be used to spatulate stones, plasters, die material, investments and alginates, ensuring thorough, dense and detailed castings and impressions. The mixer is available in various sizes to meet your specific application needs. It is also available with an insulated housing for cold applications. A built-in pump or a separate vacuum pump can be attached to the mixer.
Sublimation
Vacuum mixing helps prevent air bubbles, which can negatively impact product performance. This is especially important for solid active pharmaceutical ingredients that need to be converted into tablet, effervescent, oral or capsule formulations. The vacuum mixer deagglomerates the powders and alginates used in these preparations, as well as other materials like binders, plastics resins, jells, liquids, and epoxies.
The vertical sublimation purification apparatus includes a boat-shaped material carrier for storing the materials that will be evaporated; a heating evaporation device, which controls the temperature based on different materials and realizes evaporation; two end pipes, which are respectively sealed after air extraction to achieve an ideal sealing effect; and heat shield devices 9 formed by stuffing quartz wool into cylindrical containers made of quartz. The apparatus is capable of sustaining appropriate product purity, conducting commercial operations and producing large quantities of high-purity products with convenient operational approaches.